The Network is constituted of representative members from commissioner and provider organisations in the region as well as other affiliated organisations including
- Nottingham University Hospitals - Queens Medical Centre & City Hospital
- University Hospitals of Derby and Burton NHS Foundation Trust
- University Hospitals of Leicester NHS Trust - Leicester Royal, General & Glenfield
- Sherwood Forest Hospitals NHS Foundation Trust - Kings Mill Hospital
- United Lincolnshire Hospitals NHS Trust - Lincoln & Boston Hospitals
- Kettering General Hospital
- Northampton General Hospital
- Chesterfield Royal Hospital
- Independent Sector Hospitals (Circle, Spire Nottingham, Nuffield, Ramsay Health Care, Nottingham NHS Treatment Centre, Nations Healthcare, Nottingham Neurodisability Service, Nottingham Brain Injury Rehabilitation Centre)
- Commissioning Organisations for East Midlands region
- NHSE&I - Midlands and East Specialised Commissioners
- Provider Collaboratives: Leics, Northant, Rutland (LNR) and Lincs, Derbys, Notts (LDN)
- Adult Critical Care Co-Ordination and Transfer Service (ACCOTS)
- East Midlands Ambulance Service NHS Trust (EMAS)
- Affiliated Universities
- Health Protection Agency / Public Health Departments